From the ninth chapter.

13, 14. "And I heard a voice from the four horns of the golden altar which is in the presence of God, saying to the sixth angel which had the trumpet, Loose the four angels."] That is, the four corners of the earth which hold the four winds.

"Which are bound in the great river Euphrates."] By the corners of the earth, or the four winds across the river Euphrates, are meant four nations, because to every nation is sent an angel; as said the law, "He determined them by the number of the angels of God," ¹ until the number of the saints should be filled up. They do not overpass their bounds, because at the last they shall come with Antichrist.